Advanced Gas and Liquid Chromatography with Practical Troubleshooting
INTRODUCTION
Gas and Liquid Chromatography are essential analytical techniques in modern laboratories, providing high-precision separation and identification of chemical compounds. However, achieving reliable results requires not only theoretical knowledge but also practical expertise in method optimisation, instrument maintenance, and troubleshooting.
The *Advanced Gas and Liquid Chromatography with Practical Troubleshooting* course delivers a comprehensive understanding of chromatography principles, instrumentation, and advanced operational techniques. It combines theory with real-world problem-solving exercises to help participants achieve peak instrument performance, interpret results with confidence, and resolve common analytical challenges.
Through practical demonstrations, case studies, and hands-on exercises, delegates will enhance their technical competence in GC and LC operation, method development, and troubleshooting, ensuring consistent, accurate, and efficient laboratory results.
This training course will highlight:
* Fundamental and advanced principles of gas and liquid chromatography
* Sample preparation, introduction, separation, and detection methods
* Instrument calibration, optimisation, and maintenance best practices
* Practical troubleshooting for GC and LC performance issues
* Method development and validation for improved analytical accuracy
OBJECTIVES
By the end of this course, delegates will be able to:
* Understand the theoretical foundations and applications of GC and LC
* Operate chromatographic instruments effectively for various analytical needs
* Select and maintain columns, detectors, and injection systems for optimal performance
* Implement robust calibration and data acquisition procedures
* Develop, optimise, and validate chromatographic methods
* Troubleshoot common performance issues and restore operational efficiency
* Apply ISO 17025 accreditation principles in chromatographic analysis
TRAINING METHODOLOGY
This programme is **interactive and hands-on**, combining:
* Instructor-led technical presentations
* Practical equipment demonstrations
* Problem-solving workshops with real-world data
* Case studies from analytical laboratories
* Group discussions and Q\&A sessions
ORGANISATIONAL IMPACT
Organisations will benefit from:
* Improved laboratory efficiency and reliability of analytical results
* Reduced downtime through effective troubleshooting and maintenance
* Enhanced compliance with international standards (e.g., ISO 17025)
* More competent and confident laboratory personnel
* Cost savings through optimised equipment operation and extended component life
PERSONAL IMPACT
Participants will:
* Gain confidence in operating and optimising GC and LC systems
* Acquire practical troubleshooting techniques to solve analytical challenges
* Develop skills in method development and performance validation
* Understand the full workflow from sample preparation to final reporting
* Improve career prospects with advanced chromatographic expertise
WHO SHOULD ATTEND?
This course is ideal for:
* Laboratory technicians and analysts
* Quality control and assurance personnel
* Research and development scientists
* Laboratory managers and supervisors
* Professionals responsible for chromatographic method development and validation
COURSE OUTLINE
**DAY 1: Introduction to Chromatography**
* History and evolution of GC and LC
* Overview of modern chromatographic systems
* Factors affecting retention and selectivity
* Stationary phase loading and performance effects
* Chromatography terminology and nomenclature
**DAY 2: Chromatography Fundamentals**
* Sample preparation and introduction techniques
* Role and maintenance of injection ports in GC
* Impact of sample introduction on analytical quality
**DAY 3: Columns – Selection, Operation, and Maintenance**
* Column roles in GC and LC operations
* Criteria for selecting appropriate columns
* Column maintenance and its effect on performance
**DAY 4: GC Operation and Optimisation**
* Peak dispersion in chromatographic columns
* Detector types, selection, and maintenance
* Operational setup and routine checks
* Sampling techniques for reproducible results
**DAY 5: Data Acquisition and Calibration**
* Calibration methods and their link to accuracy
* Data acquisition systems and processing workflows
* Ensuring calibration integrity for consistent performance
**DAY 6: Applications and Troubleshooting**
* Chromatography applications in various industries
* Method development for GC and LC
* Troubleshooting common operational issues
* Case studies in problem-solving
**DAY 7: Quality Standards and Laboratory Management**
* ISO 17025 accreditation principles for chromatography
* Best practices in laboratory management
* Integrating troubleshooting into daily operations
CERTIFICATES
On successful completion, delegates will receive:
* A **KELeaders Certificate of Completion**
* **CPD Certification** (1 CPE credit per 50 minutes of training)
* A personalised CPD certificate compliant with international CPD standards
Enquiries and Registration
Enquiry at : admin@keleaders.com
Whatsapp: 0044 790 125 9494
For more details visit our website : www.keleaders.com
